Motrin (ibuprofen): What it does and how to use it safely

Motrin is a brand name for ibuprofen, a common NSAID used for pain, fever, and inflammation. It works fast for headaches, muscle aches, menstrual cramps, and minor injuries. People like it because it’s available over the counter and usually works better than acetaminophen for swelling-related pain.

How to use Motrin safely

For adults, typical over-the-counter doses are 200–400 mg every 4–6 hours as needed. Don’t exceed 1,200 mg per day without a doctor’s advice. Doctors sometimes prescribe higher doses (up to 2,400 mg/day) for specific problems—only under medical supervision.

For children, dose by weight: about 10 mg per kg every 6–8 hours, with a max of 40 mg/kg per day. Use the measuring device that comes with the medicine. If you’re unsure, check the package or ask your pediatrician.

Simple safety tips: take Motrin with food or milk to cut stomach upset, use the lowest dose that helps, and keep treatment as short as possible. Don’t combine Motrin with other NSAIDs (like naproxen) or with extra-strength aspirin unless a doctor tells you to.

Watch over-the-counter labels—many cold and flu products also contain ibuprofen. Accidentally taking two products with ibuprofen can push you past safe limits.

Key risks, interactions, and who should avoid it

Ibuprofen can irritate the stomach and increase bleeding risk, especially if you have a history of ulcers or take blood thinners (warfarin, direct oral anticoagulants). It can also raise blood pressure and affect kidney function, so avoid regular use if you have chronic kidney disease, uncontrolled high blood pressure, or heart failure unless your doctor approves.

Drug interactions to watch for: blood thinners, certain blood pressure drugs (ACE inhibitors, ARBs, diuretics), lithium, and methotrexate. If you’re on prescription meds, check with your pharmacist or doctor before using Motrin regularly.

Pregnancy note: avoid ibuprofen in the third trimester. Talk to your OB before taking it in early pregnancy.

Serious allergic reactions and asthma worsening can happen in some people. Stop Motrin and seek urgent care if you get hives, swelling, trouble breathing, or sudden severe stomach pain.

Want to buy Motrin online? Use licensed pharmacies, check for an active address and pharmacist contact, and avoid suspiciously cheap or foreign sites. For chronic pain, see your doctor so you get a safe plan—not just long-term OTC use.

Practical rule: lowest effective dose for the shortest time, check drug labels, and ask a clinician if you have heart, kidney, stomach, or pregnancy concerns. That keeps Motrin useful without unnecessary risk.

This page gives general information and doesn’t replace personalized medical advice. When in doubt, call your healthcare provider.