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Tag: pharmacogenomics

Azathioprine and TPMT Testing: How Genetic Screening Prevents Life-Threatening Side Effects

Azathioprine and TPMT Testing: How Genetic Screening Prevents Life-Threatening Side Effects

Daniel Whiteside Jan 19 13 Comments

Azathioprine is a cost-effective immunosuppressant, but it can cause life-threatening blood cell damage in people with genetic enzyme deficiencies. TPMT and NUDT15 testing before starting the drug can prevent severe side effects like myelosuppression and liver toxicity.

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